Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch_repos |
| Phenotype | phenotype_truncNotch_versus_wtNotch.cls#wtNotch_versus_truncNotch_repos |
| Upregulated in class | wtNotch |
| GeneSet | NCI_AURORA B SIGNALING |
| Enrichment Score (ES) | 0.7418512 |
| Normalized Enrichment Score (NES) | 1.8234187 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.09248231 |
| FWER p-Value | 0.066 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | NCAPH | 6220435 | 56 | 3.183 | 0.1231 | Yes | ||
| 2 | CUL3 | 1850520 | 446 | 2.066 | 0.1841 | Yes | ||
| 3 | NSUN2 | 2120193 | 517 | 1.961 | 0.2580 | Yes | ||
| 4 | RASA1 | 1240315 | 523 | 1.945 | 0.3348 | Yes | ||
| 5 | NCL | 2360463 4540279 | 591 | 1.866 | 0.4051 | Yes | ||
| 6 | NDC80 | 4120465 | 867 | 1.583 | 0.4530 | Yes | ||
| 7 | KIF23 | 5570112 | 1019 | 1.409 | 0.5007 | Yes | ||
| 8 | CDCA8 | 2340286 6980019 | 1114 | 1.320 | 0.5480 | Yes | ||
| 9 | AURKA | 780537 | 1317 | 1.140 | 0.5823 | Yes | ||
| 10 | INCENP | 520593 | 1387 | 1.082 | 0.6214 | Yes | ||
| 11 | PPP2R5D | 4010156 380408 5550112 5670162 | 1582 | 0.982 | 0.6499 | Yes | ||
| 12 | CENPA | 5080154 | 1872 | 0.803 | 0.6662 | Yes | ||
| 13 | BIRC5 | 110408 580014 1770632 | 1894 | 0.790 | 0.6963 | Yes | ||
| 14 | STMN1 | 1990717 | 2167 | 0.636 | 0.7069 | Yes | ||
| 15 | SMC2 | 4810133 | 2389 | 0.548 | 0.7167 | Yes | ||
| 16 | SMC4 | 5910240 | 2448 | 0.524 | 0.7344 | Yes | ||
| 17 | AURKB | 5890739 | 2647 | 0.458 | 0.7419 | Yes | ||
| 18 | EVI5 | 6380040 | 2920 | 0.367 | 0.7418 | No | ||
| 19 | PPP1CC | 6380300 2510647 | 3376 | 0.251 | 0.7272 | No | ||
| 20 | KLHL13 | 6590731 | 5319 | 0.059 | 0.6251 | No | ||
| 21 | KIF2C | 6940082 | 6866 | 0.018 | 0.5426 | No | ||
| 22 | BUB1 | 5390270 | 8457 | -0.009 | 0.4574 | No | ||
| 23 | NPM1 | 4730427 | 9124 | -0.020 | 0.4224 | No | ||
| 24 | CBX5 | 3830072 6290167 | 9360 | -0.024 | 0.4107 | No | ||
| 25 | SGOL1 | 1980075 5220092 6020711 | 10214 | -0.040 | 0.3664 | No | ||
| 26 | DES | 1450341 | 10230 | -0.041 | 0.3672 | No | ||
| 27 | PSMA3 | 5900047 7040161 | 10440 | -0.045 | 0.3577 | No | ||
| 28 | AURKC | 4060687 | 11384 | -0.069 | 0.3097 | No | ||
| 29 | MYLK | 4010600 7000364 | 13035 | -0.144 | 0.2266 | No | ||
| 30 | KIF20A | 2650050 | 13526 | -0.183 | 0.2075 | No | ||
| 31 | VIM | 20431 | 14039 | -0.235 | 0.1893 | No | ||
| 32 | RACGAP1 | 3990162 6620736 | 15208 | -0.437 | 0.1438 | No | ||
| 33 | RHOA | 580142 5900131 5340450 | 16637 | -0.998 | 0.1065 | No |
